Nick Sutcliffe - August 22, 2025

Patent Strategies for Cell-based Therapeutics

Securing robust patent protection for cell-based therapeutics presents unique challenges, ...

Eliot Ward - August 13, 2025

Mitochondria: the secret to regenerating human tissue?

Istesso co-founder Lisa Patel is researching how to regenerate and repair tissue by modulating ...

Adam Gregory - July 29, 2025

Event - From Innovation to Impact: Resolving Pinch Points in Cell and Gene Therapies, 23 July

On Wednesday 23 July, we were delighted to host our panel discussion and networking event "From ...

Laura Carney - July 28, 2025

Leucid Bio: the next generation of CAR T-cell therapies

CAR T-cell therapies hold the promise of curing solid tumour cancers. Dr John Maher, Chief ...

Katie Dale - May 21, 2025

Couriers for Cures: The Next Generation of Delivery Methods for Gene Therapy

A record number of gene therapies achieved regulatory approval in 2024, transforming how biopharma ...

Adam Gregory - March 19, 2025

In vivo Cell Therapy: Breaking Free of the Chains of Ex Vivo Engineering

In vivo cell therapy is emerging as a groundbreaking approach to reduce the cost and expand the ...

Edward Couchman - March 11, 2025

Discontinuous Epitope Claims get Green Light in Europe

Patents for antibodies defined by discontinuous epitopes have garnered a lot of attention recently. ...

Adam Gregory - March 7, 2025

Hummingbird Bioscience’s multi-payload ADC technology licensed by Callio Therapeutics

We are delighted to congratulate our client Hummingbird Bioscience on the successful out-licensing ...

Nick Sutcliffe - March 3, 2025

Oncolytic Virotherapy (OVT) – A Technology Finally Coming of Age?

The potential of viruses to selectively infect and kill cancer cells was first recognised over a ...

Katherine Collins - February 19, 2025

Revolutionising Immunotherapy: The Promise of TCR T-Cells

For the past 10 years or so, the focus in the adoptive T-cell therapy space has been on chimeric ...

Anna Mudge - October 29, 2024

GENE-ius options to protect gene therapies

Gene therapies involve treating patients by manipulating their genetic makeup. Such therapies may ...

Fay Allen - September 12, 2024

Dr. Maike de la Roche: immunotherapy & thriving as a woman in science

The world-renowned pioneer in immunotherapy tells Mewburn Ellis about her work with CAR-T cells, ...

Adam Gregory - August 13, 2024

‘It’s a 50% reduction in ageing’

Singapore startup VVB Bio promises a dramatic reduction in ageing via a single jab. Now out of ...

Katherine Collins - April 2, 2024

Efficiency in Expansion: Meeting the Scale-Up Challenge in Cell and Gene Therapies

One of the pivotal challenges in the development and commercialisation of cell and gene therapies ...

Fay Allen - March 27, 2024

Endometriosis - research, diagnosis and treatment progress

March is Endometriosis Action Month, and this year’s focus is on raising awareness.

Katie Dale - February 26, 2024

Top marks for Iovance as FDA approves first-in-class cell therapy Amtagvi for solid tumours

On February 16, 2024, a real milestone was reached in the cell therapy field, as the FDA approved ...

Frances Salisbury - February 8, 2024

Yoni Health: the medical secrets of menstrual blood

Menstrual effluent contains a wealth of scientific info, including biomarkers for endometriosis, ...

Edward Couchman - February 7, 2024

Genes as Medicines: Treating the Untreatable

In 2023, gene therapy hit the headlines in the UK, when the BBC reported the cure of a toddler with ...

Alex Galbraith - November 17, 2023

The first CRISPR treatment – Casgevy wins UK approval for sickle cell disease

In a world first, the UK medicines regulator has given the green light to a therapy employing ...

Katie Dale - November 6, 2023

Swapping in stem cells for diabetes treatment

With just under 50% of type 1 diabetes patients using wearable blood glucose monitors1, medical ...

Amelia Jones - September 5, 2023

A leap forward in slowing down Alzheimer’s

This summer has seen a major leap forward in slowing the rate of progression of Alzheimer’s disease.

Alex Galbraith - September 1, 2023

Gene therapy – the status quo and future trends

The uptick in recent approvals in the gene therapy space is emblematic of a field which is now ...

Fay Allen - August 10, 2023

In vivo expression of chimeric antigen receptors: using gene therapy to improve cell therapy

In vivo CAR therapies build on the success of standard CAR treatments and aim to overcome the ...

Anna Mudge - August 9, 2023

The next-generation therapies for autoimmune diseases

The immune system has an extraordinary capacity to distinguish “self” from “non-self”. This means ...

Edward Couchman - August 7, 2023

Cells as medicines: the promise of cell therapy

Cell therapy is one of the most exciting areas of medical science, with recent years having seen ...

Nick Sutcliffe - July 26, 2023

IP priorities for forward-looking cell and gene therapy businesses

IP priorities are especially important to businesses developing advanced therapeutic products. ...

Anna Mudge - May 4, 2023

The allogeneic advantage

Bespoke cell therapies are expensive and time-consuming. Now allogeneic cell treatments offer a ...

Anna Mudge - March 21, 2023

Advanced Therapies Congress 2023 - five key themes

Anna Mudge enjoyed a bustling two days at the Advanced Therapies Congress 2023 in London. Nine ...

Anna Mudge - February 20, 2023

Trafficking T cells – how to get cells to their target destination

After being in the shadow of its famous relative, the antibody-producing B cell, for many decades, ...

Katie Dale - January 21, 2023

CAR Treg cell therapy - to autoimmunity and beyond

A new wave of cell therapy is hitting the clinics for treating various autoimmune diseases, by ...

Fay Allen - March 8, 2022

We need to talk about women's health - spotlight on endometriosis

Women’s health is an area that has suffered from gender bias for years. One reason for this is that ...

Daniel Yin - July 28, 2021

Senolytics are knock, knock, knocking on ageing’s door

In 1974, Bob Dylan asked that we stay forever young. Today, exciting developments in the longevity ...

Joseph Morgan - July 19, 2021

First human in vivo CRISPR/Cas9 gene editing results make history

The ability to directly edit a patient’s genome safely and efficiently to treat genetic diseases ...

Samuel Hart - June 30, 2021

Circulating tumour cells: at the forefront of cancer diagnosis and treatment

In cancer patients, “metastasis” occurs as tumour cells break-away from the site at which they are ...

Edward Couchman - June 15, 2021

Cell therapy: repairing and rebuilding the body

Recent advances in medicine have, for the first time, allowed physicians to directly intervene in ...

Adam Gregory - April 19, 2021

Jim Mellon: the reluctant gradualist taking on ageing

Forward editor Caitlin Mackesy Davies learns how we might all be able to live long and prosper from ...

Isobel Stone - April 7, 2021

Need to know: are we set for a bioprinting boom?

From refashioning foods to fabricating organs, bioprinting is the smart technology that could have ...

Lucy White - March 31, 2021

The future of organ transplantation: growing organs from scratch?

Organ transplantation has saved, transformed, and extended countless lives. Although ...

Frances Salisbury - September 10, 2020

Neoantigens: IP considerations for an emerging class of cancer immunotherapy

Recent cell and gene therapy product approvals have allowed the pharmaceutical industry to start a ...

Rebecca Tollervey - June 25, 2020

Cellular immunity – a contributor to COVID-19 “dark matter”?

Immunologist Karl Friston of University College London has theorized that there may be ...

Anna Mudge - March 31, 2020

Neoantigen-targeted adoptive cell therapies – the next frontier in cancer immunotherapy

Cancer immunotherapies harness the power of the patient’s immune system to destroy malignant cells ...

Eliot Ward - December 6, 2019

Gamma/delta T cells emerge as an untapped resource for cancer immunotherapy

Third lymphocyte lineage shows its mettle B lymphocytes, a type of white blood cell that is ...

Adam Gregory - September 26, 2019

T cell engagers - dark horses of immunotherapy

Chimeric antigen receptor (CAR) technology has attracted a lot of attention and investment in ...